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杜昌益 教授
杜昌益 教授
Chang-Yih Duh, Professor

Ph.D.(1986)University of Illinois at Medical Center

*海洋資源學系教 授(1996起)
 Associate Professor,1994.8

Isolation, identification, structure elucidation and bioassay of biologically active marine and terrestrial natural product.
Constituents, in particular those with anticancer, antiviral, and antiplatelet aggregation activities.
Important awards
84school year,《University research merit award》


A. Journal Papers: 
1. Shi-Yie Cheng, Shang-Kwei Wang, Pei-Wen Chen, Chang-Yih Duh (2015, Apr). Sandensone A, a novel sesquiterpenoid from the Formosan soft coral Sinularia sandensis. Bioorganic & Medicinal Chemistry Letters, 25, 2353-2355. 本人為通訊作者.
2. Lee, HP; Lin, YY; Duh, CY; Huang, SY ; Wang, HM ; Wu, SF; Lin, SC; Jean, YH; Wen, ZH (2015, Feb). Lemnalol attenuates mast cell activation and osteoclast activity in a gouty arthritis model. JOURNAL OF PHARMACY AND PHARMACOLOGY, 67 (2); 274-285.
3. Yen-Ju Tseng, Yuan-Chien Yang, Shang-Kwei Wang and Chang-Yih Duh (2014, Jun). Numerosol A–D, New Cembranoid Diterpenes from the Soft Coral Sinularia numerosa. Mar. Drugs , 3371-3380. 本人為通訊作者.
4. Shi-Yie Cheng, Neng-Lang Shih, Cheng-Ta Chuang, Shu-Fen Chiou, Chia-Ning Yang, Shang-Kwei Wang, Chang-Yih Duh (2014, Feb). Sinugyrosanolide A, an unprecedented C-4 norcembranoid, from the Formosan soft coral Sinularia gyrosa. Bioorganic & Medicinal Chemistry Letters , 1562–1564. 本人為通訊作者.
5. Shi-Yie Cheng, Neng-Lang Shih, Kuang-Yu Hou, Mang-Jye Ger, Chia-Ning Yang, Shang-Kewi Wang, Chang-Yih Duh (2014, Jan). Kelsoenethiol and dikelsoenyl ether, two unique kelsoane-type sesquiterpenes, from the Formosan soft coral Nephthea erecta. Bioorganic & Medicinal Chemistry Letters , 473– 475. 本人為通訊作者.
6. Shin-Rung Lin, Meei Jyh Jiang, Hung-Hsueh Wang, Cheng-Hui Hu, Ming-Shan Hsu, Edward Hsi, Chang-Yih Duh,Shang-Kwei Wang (2013, Nov). Human Cytomegalovirus UL76 Elicits Novel Aggresome Formation via Interaction with S5a of the Ubiquitin Proteasome System. Journal of Virology, 2013, 87(21):11562-78.
7. Shang-Kwei Wang, Mu-Keng Hsieh and Chang-Yih Duh (2013, Oct). New Diterpenoids from Soft Coral Sarcophyton ehrenbergi. Mar. Drugs , 4318-4327. 本人為通訊作者.
8. Wen-Chi Wei, Ping-Jyun Sung, Chang-Yih Duh, Bo-Wei Chen, Jyh-Horng Sheu and Ning-Sun Yang (2013, Oct). Anti-Inflammatory Activities of Natural Products Isolated from Soft Corals of Taiwan between 2008 and 2012. Mar. Drugs , 4083-4126.
9. Yen-Ju Tseng, Shang-Kwei Wang and Chang-Yih Duh (2013, Aug). Secosteroids and Norcembranoids from the Soft Coral Sinularia nanolobata. Mar. Drugs , 3288-3296. 本人為通訊作者.
10. Yen-Ju Tseng, Yu-Sheng Lee, Shang-Kwei Wang, Jyh-Horng Sheu and Chang- Yih Duh (2013, Jul). Parathyrsoidins A–D, Four New Sesquiterpenoids from the Soft Coral Paralemnalia thyrsoides. Mar. Drugs , 2501-2509. 本人為通訊作者.

執行之研究計劃(research projects):
1. 抗菌及抗病毒海洋天然物之開發(102-2320-B-110-003-MY3) 2013/08/01~2016/07/31
2. 九種軟珊瑚生物活性成分之研究(99-2628-B-110-002-MY3) 2010/08/01~2013/07/31